Analysis of potential interaction of spindle matrix proteins and the motor protein Ncd in Drosophila
نویسندگان
چکیده
iii CHAPTER 1. GENERAL INTRODUCTION 1 Thesis organization 1 CHAPTER 2. LITERATURE REVIEW 3 Mitotic spindle 3 Motor proteins 12 Spindle matrix 18 CHAPTER 3. ANALYSIS OF POTENTIAL INTERACTION BETWEEN SPINDLE MATRIX PROTEINS AND THE MOTOR PROTEIN NCD 24 Abstract 24 Introduction 25 Methods 26 Results 33 Discussion 36 Table and Figures 39 CHAPTER 4. CONCLUSIONS AND PROSPECTIVE 49 CHAPTER 5. REFERENCES 52 ACKNOWLEDGEMENTS 67
منابع مشابه
Mutants of the microtubule motor protein, nonclaret disjunctional, affect spindle structure and chromosome movement in meiosis and mitosis.
The Drosophila microtubule motor protein, nonclaret disjunctional (ncd), is required for proper chromosome distribution in meiosis and mitosis. We have examined the meiotic and mitotic divisions in wild-type Drosophila oocytes and early embryos, and the effects of three ncd mutants (cand, ncd and ncdD) on spindle structure and chromosome movement. The ncd mutants cause abnormalities in spindle ...
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